DVT Prophylaxis After Total Hip and Knee Replacement

DVT Prophylaxis After Total Hip and Knee Replacement

By William P Barrett, MD

In an article published January 18, 2017, in the journal Bone and Joint Surgery, Dr. J. Parvizi and coauthors reported on their study evaluating the effectiveness of low-dose (81 mg aspirin twice a day) to standard-strength aspirin (325 mg twice a day). In a prospective study involving over 4,600 total joint cases, they found low-dose aspirin was equivalent to standard-strength aspirin in preventing DVT and pulmonary embolus after hip and knee replacement. This marks on important study demonstrating the efficacy of low-dose aspirin in preventing blood clots in the lower extremities after joint replacement. The lower dose aspirin should have a lower side effect profile, including GI irritation and bleeding. Based on this and other studies, we plan on switching from our standard-strength aspirin to low-dose aspirin for treatment of patients with low risk for blood clots following joint replacement surgery at Valley Medical Center.

About The Author

William Barrett, MD is a fellowship trained orthopedic surgeon who specializes in primary and revision hip and knee replacement. He performs over 500 hip and knee replacement procedures each year. He is actively involved in clinical research on Anterior Approach Total Hip Replacement (THA), Alternative Bearings for THA, Less Invasive Approaches to joint replacement and use of computerized vs. custom cutting guides for knee replacement. As a nationally recognized joint replacement surgeon, he lectures globally on hip and knee replacement topics. He is active in the American Academy of Orthopaedic Surgeons Continuing Medical Education programs. He is a board examiner for the American Board of Orthopaedic Surgery.