In a recent article in Arthritis Research and Therapy, authors noted the significant relationship between obesity, as defined by a body mass index greater than 30 and the risk of developing arthritis requiring hip and knee replacement. The authors found that increased weight, abdominal circumference and body mass index were associated with the development of osteoarthritis. A research team headed by Dr. Cicuttini of Monash University in Melbourne, Australia, conducted the prospective study on 32,023 healthy volunteers to examine the relationship between different adiposity measures and the risks of subsequent primary knee and hip replacement surgery. The study determined there was a three to four fold risk of joint replacement associated with elevated body weight, BMI, fat mass, and percentage of fat. It is felt that adipose or fat mass continue to increase joint loading, which may increase the risk of osteoarthritis progression and subsequent joint replacement.